| Characteristic | Details |
|---|---|
| Active Ingredient | Tadalafil |
| Dosage Form | Tablet |
| Available Dosages | 20mg |
| Administration Route | Oral |
| Duration of Action | Up to 36 hours |
| Common Side Effects | Headache, indigestion, back pain |
| Target Group | Adults |
| Learn More | |
Mechanism of Action
Cialis Professional functions as a potent inhibitor of phosphodiesterase type 5 (PDE5). This enzyme modulation enhances blood flow. Vasodilation occurs due to the increase of cyclic guanosine monophosphate (cGMP). Erectile dysfunction treatment relies on this process. The release of nitric oxide (NO) catalyzes cGMP production. The result is a sustained erection.
Tadalafil 20mg increases cGMP levels. The primary effect is smooth muscle relaxation. This occurs within the corpus cavernosum. Improved arterial blood inflow is the outcome. Outflow of blood decreases due to venous constriction. Such a mechanism supports sexual function.
The half-life of tadalafil extends to approximately 17.5 hours. This facilitates an extended duration of action. The effective treatment window is up to 36 hours. Such prolonged effectiveness offers flexibility. It differentiates Cialis Professional from its peers.
Cialis Professional Contraindications
Contraindications for Cialis Professional require attention. Severe cardiovascular disorders preclude its use. This includes unstable angina and recent myocardial infarction. Patients with hypotension should avoid it. Severe hepatic impairment is another contraindication.
Nitrate use is incompatible with tadalafil 20mg. The interaction may precipitate hypotension. Alpha-blockers may also pose risks. Combination with PDE5 inhibitors is discouraged. The contraindication list ensures safety.
Individuals with retinal disorders should exercise caution. Non-arteritic anterior ischemic optic neuropathy (NAION) is a concern. Those with hereditary retinal degeneration need vigilance. Always consult healthcare providers.
Cialis Professional Interactions
Drug interactions affect Cialis Professional efficacy. Concomitant use with nitrates leads to complications. Nitric oxide donors exhibit similar risks. Careful consideration is necessary when co-administering.
Strong CYP3A4 inhibitors alter tadalafil levels. Medications like ketoconazole affect drug metabolism. Ritonavir may increase tadalafil plasma concentration. Patients should disclose all current medications.
Alcohol consumption may intensify tadalafil effects. This results in decreased blood pressure. Syncope and dizziness could follow. Moderation is advised during treatment.
Toxicity
Tadalafil overdose demands immediate attention. Symptoms include prolonged erection or priapism. Gastrointestinal disturbances may occur. Cardiovascular events like arrhythmia are possible. Urgent medical care is critical.
Clinical trials evaluated tadalafil safety. No fatalities linked to overdose were reported. However, vigilance remains vital. Proper dosing mitigates risks.
Animal studies show no significant teratogenicity. Tadalafil is classified under pregnancy category B. Nonetheless, prescribers must weigh potential risks. Clinical judgment should guide therapeutic decisions.
Is Non-Prescription Cialis Professional Available?
Cialis Professional requires a prescription. Regulatory bodies mandate this status. Tadalafil is potent and necessitates medical oversight. Appropriate patient assessment precedes dispensing.
Online availability may suggest otherwise. Consumers must exercise caution. Unregulated sources pose health risks. Authentic products ensure efficacy and safety.
Consult healthcare professionals for erectile dysfunction. Customized treatment strategies optimize outcomes. Medical history and concurrent conditions dictate therapy. Supervised usage aligns with best practices.
Information taken from:
- https://concienciagenerativa.com/forsta-lampligheten-av-intranasalt-influensavaccin-och-antibiotikaanvandning/
- https://thegyk.com/2024/05/18/ra-rheumatoid-arthritis-and-eye-health/
- https://jjnoorzad.ad-wize.net/fibromyalgia-exploring-gastrointestinal-motility-management/
- https://dev-b2m.pantheonsite.io/invasive-candidiasis-a-medical-perspective/
- https://jogjaaudioschool.com/jamfora-vaccinationsfordelar-tdap-vs-vattkoppor-i-modern-sjukvard/
- https://hvac.askujjwall.com/exploring-asceniv-a-new-hope-for-hyperaldosteronism-treatmen/
- https://observatorio.regiontumbes.gob.pe/veroxil-un-gran-avance-en-el-tratamiento-de-infecciones-bacterianas-resistentes/
- https://www.franbrea.com/2024/02/15/utforsker-megestrol-acetates-potensiale-mot-filovirusinfeksjoner/
- https://kgisimmigration.com/2024/07/03/chlamydia-psittaci-infection-an-internal-medicine-perspective/
- https://www.5020waterloord.com/trimethadione-tablets-exploring-breast-cancer-treatment-options/
- https://clinicamedicavivere.com/utforska-zalcitabines-roll-i-toxoplasmosis-toxoplasma-infection-treatmen/
